Stronger with

Pycnogenol® was shown to help with nitric oxide (NO) production, blood circulation and blood flow to the muscles; which in turn helps the body achieve peak muscle performance and speeds recovery after exercise.

Why Pycnogenol® may play an important role with physical activity?

The link between Pycnogenol® and sports endurance was first studied several years ago at California State University. Recreational athletes showed an increase of athlete endurance while supplementing with Pycnogenol® as compared to endurance recorded from participants 

taking the placebo.


In a double-blind, placebo-controlled, crossover study design, recreational athletes were supplemented with either Pycnogenol® or placebo for 30 days and were then crossed over to the other group for an additional 30 days.

The athletes performed under controlled conditions on a treadmill with individual settings adjusted to 85% of a person’s maximum oxygen consumption to prevent too rapid exhaustion and reduce anaerobic metabolism. Results of the study showed a statistically significant increase of athlete endurance while taking Pycnogenol® as compared to endurance recorded from

participants taking the placebo.

Pycnogenol® for Sport - Animated Infographic

How Pycnogenol® helps relax blood vessels and improves blood flow?

Pycnogenol® stimulates the enzyme “endothelial nitric oxide synthase” (eNOS) for enhanced generation of NO from the precursor molecule L-arginine.


Pycnogenol increases endurance aids in muscle recovery and alleviates cramping

An increase in physical activity can lend itself to sore muscles and fatigue which

can take several days to subside.


Pycnogenol® was shown to significantly reduce muscular pain and cramps in athletes and healthy, normal individuals. Poor circulation in the muscle is known to cause cramps and the antioxidant improved the cramping in patients due to a stimulation of blood flow to their muscle tissue.


The findings indicate that Pycnogenol® can play an important role in sports by improving blood flow to the muscles and hastening post-exercise recovery. This is great news to

the millions of athletes worldwide and extremely significant for all individuals

interested in muscle cramp and pain relief with a natural approach.


Pycnogenol lowers muscular pain in sports and enhances blood microcirculation,

blood flow and oxygenation of muscle

Two clinical studies have shown that Pycnogenol® causes vasodilatation and consequently improves blood micro-circulation. An increased presence of oxygen and decreased carbon dioxide after consumption of Pycnogenol® was shown. Pycnogenol® contributes to better blood flow and oxygenation of muscle.

What is Sarcopenia?

Copyright © 2022 Horphag Research supplies Pycnogenol® as a raw material to companies that produce a variety of Pycnogenol®-containing products. Horphag Research does not make any claims regarding the use of these finished products and each manufacturer is 

responsible for ensuring that the claims made for and use of its products comply with the regulatory requirement of the 

locations in which it markets its products.



*For a complete list of scientific research and further information visit our website at www.pycnogenol.com. Pycnogenol®, French maritime pine bark extract, is a registered trademark of Horphag Research, Ltd and its applications are protected by U.S. patents and other international patents. ©2021 Horphag Research 


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, 

cure, or prevent any disease.